Port of San Diego schedule

Cruises from San Diego in April 2027

We list 17 departures from the Port of San Diego in April 2027, which is about normal for San Diego. The ships are Disney Wonder, Eurodam, Koningsdam, Nieuw Amsterdam, Serenade of the Seas, and Zaandam.

Trips run from 3 to 13 nights. Between them they cover Baja California and Ensenada, the Pacific coast, and the Mexican Riviera and the Sea of Cortez.

Serenade of the Seas on Thu, Apr 15, 2027 has the lowest starting fare this month, $364.06 per person. Every sailing here has a confirmed itinerary. The port's own schedule shows a few more ships than we do, mostly ones that only stop here partway through a longer voyage.

Departures: 17
Ships: 6
Length: 3 to 13 nights
From: $364.06

Schedule last updated 2026-10-23 · 17 departures listed · Dates can change. Verify with the cruise line before booking.

Cruises departing the Port of San Diego in April 2027
Departs	Ship	Line	Nights	Itinerary & ports	From
Fri, Apr 2, 2027 backWed, Apr 7, 2027	Disney Wonder	Disney Cruise Line	5	5-Night Baja Mexico Calls at Cabo San Lucas (Mexico) · Ensenada (Mexico)	from $1,522 $304 a night · per person interior, as of 2026-10-23
Sat, Apr 3, 2027 endsWed, Apr 7, 2027	Koningsdam	Holland America Line	4	4-Night U.S. Pacific Coast Calls at Victoria (British Columbia) Ends in Vancouver (British Columbia)	from $399 $100 a night · per person interior, as of 2026-10-23
Sun, Apr 4, 2027 backThu, Apr 8, 2027	Serenade of the Seas	Royal Caribbean International	4	4-Night Catalina & Ensenada Calls at Catalina Island (California) · Ensenada (Mexico)	from $402 $101 a night · per person interior, as of 2026-10-23
Sun, Apr 4, 2027 backSat, Apr 17, 2027	Zaandam	Holland America Line	13	13-Night Mexico Calls at Cabo San Lucas (Mexico) · Guaymas (Mexico) · Topolobampo (Mexico) · La Paz (Mexico) · Mazatlán (Mexico) · Puerto Vallarta (Mexico) · Manzanillo (Mexico) · Ensenada (Mexico)	from $1,299 $100 a night · per person interior, as of 2026-10-23
Thu, Apr 8, 2027 backSun, Apr 11, 2027	Serenade of the Seas	Royal Caribbean International	3	3-Night Ensenada Calls at Ensenada (Mexico)	from $378.34 $126 a night · per person lowest available fare, as of 2026-10-23
Sun, Apr 11, 2027 backThu, Apr 15, 2027	Serenade of the Seas	Royal Caribbean International	4	4-Night Catalina & Ensenada Calls at Catalina Island (California) · Ensenada (Mexico)	from $693 $173 a night · per person suite, as of 2026-10-23
Wed, Apr 14, 2027 backMon, Apr 19, 2027	Disney Wonder	Disney Cruise Line	5	5-Night North America Calls at Catalina Island (California) · Ensenada (Mexico)	from $1,257 $251 a night · per person interior, as of 2026-10-23
Thu, Apr 15, 2027 backSun, Apr 18, 2027	Serenade of the Seas	Royal Caribbean International	3	3-Night Ensenada Calls at Ensenada (Mexico)	from $364.06 $121 a night · per person lowest available fare, as of 2026-10-23 Lowest fare shown
Sat, Apr 17, 2027 endsFri, Apr 23, 2027	Eurodam	Holland America Line	6	6-Night U.S. Pacific Coast Calls at San Francisco (California) Ends in Vancouver (British Columbia)	from $949 $158 a night · per person balcony, as of 2026-10-23
Sat, Apr 17, 2027 endsSat, Apr 24, 2027	Zaandam	Holland America Line	7	7-Night U.S. Pacific Coast Calls at Catalina Island (California) · Santa Barbara (California) · Astoria (Oregon) · Victoria (British Columbia) Ends in Vancouver (British Columbia)	from $999 $143 a night · per person interior, as of 2026-10-23
Sun, Apr 18, 2027 backThu, Apr 22, 2027	Serenade of the Seas	Royal Caribbean International	4	4-Night Catalina & Ensenada Calls at Catalina Island (California) · Ensenada (Mexico)	from $418.5 $105 a night · per person lowest available fare, as of 2026-10-23
Mon, Apr 19, 2027 backFri, Apr 23, 2027	Disney Wonder	Disney Cruise Line	4	4-Night Baja Mexico Calls at Ensenada (Mexico)	from $973 $243 a night · per person interior, as of 2026-10-23
Thu, Apr 22, 2027 backSun, Apr 25, 2027	Serenade of the Seas	Royal Caribbean International	3	3-Night Ensenada Calls at Ensenada (Mexico)	from $381.31 $127 a night · per person lowest available fare, as of 2026-10-23
Fri, Apr 23, 2027 backFri, Apr 30, 2027	Disney Wonder	Disney Cruise Line	7	7-Night Baja Mexico Calls at Puerto Vallarta (Mexico) · Cabo San Lucas (Mexico) · Ensenada (Mexico)	from $1,554 $222 a night · per person interior, as of 2026-10-23
Sun, Apr 25, 2027 backSun, May 2, 2027	Serenade of the Seas	Royal Caribbean International	7	7-Night Ensenada, Cabo & La Paz Calls at La Paz (Mexico) · Cabo San Lucas (Mexico) · Ensenada (Mexico)	from $659 $94 a night · per person interior, as of 2026-10-23
Wed, Apr 28, 2027 endsSun, May 2, 2027	Nieuw Amsterdam	Holland America Line	4	4-Night U.S. Pacific Coast Calls at Victoria (British Columbia) Ends in Vancouver (British Columbia) Sources disagree, verify with the line	from $429 $107 a night · per person interior, as of 2026-10-23
Fri, Apr 30, 2027 backThu, May 6, 2027	Disney Wonder	Disney Cruise Line	6	6-Night Baja Mexico Calls at Cabo San Lucas (Mexico) · Ensenada (Mexico)	from $1,366 $228 a night · per person interior, as of 2026-10-23

APR
2
Friday · 5 nights
5-Night Baja Mexico
Disney Wonder · Disney Cruise Line
Calls at Cabo San Lucas (Mexico) · Ensenada (Mexico)
Returns Wed, Apr 7, 2027
from $1,522 $304 a night · per person
interior, as of 2026-10-23
APR
3
Saturday · 4 nights
4-Night U.S. Pacific Coast
Koningsdam · Holland America Line
Calls at Victoria (British Columbia)
Ends in Vancouver (British Columbia)
Ends Wed, Apr 7, 2027 in Vancouver
from $399 $100 a night · per person
interior, as of 2026-10-23
APR
4
Sunday · 4 nights
4-Night Catalina & Ensenada
Serenade of the Seas · Royal Caribbean International
Calls at Catalina Island (California) · Ensenada (Mexico)
Returns Thu, Apr 8, 2027
from $402 $101 a night · per person
interior, as of 2026-10-23
APR
4
Sunday · 13 nights
13-Night Mexico
Zaandam · Holland America Line
Calls at Cabo San Lucas (Mexico) · Guaymas (Mexico) · Topolobampo (Mexico) · La Paz (Mexico) · Mazatlán (Mexico) · Puerto Vallarta (Mexico) · Manzanillo (Mexico) · Ensenada (Mexico)
Returns Sat, Apr 17, 2027
from $1,299 $100 a night · per person
interior, as of 2026-10-23
APR
8
Thursday · 3 nights
3-Night Ensenada
Serenade of the Seas · Royal Caribbean International
Calls at Ensenada (Mexico)
Returns Sun, Apr 11, 2027
from $378.34 $126 a night · per person
lowest available fare, as of 2026-10-23
APR
11
Sunday · 4 nights
4-Night Catalina & Ensenada
Serenade of the Seas · Royal Caribbean International
Calls at Catalina Island (California) · Ensenada (Mexico)
Returns Thu, Apr 15, 2027
from $693 $173 a night · per person
suite, as of 2026-10-23
APR
14
Wednesday · 5 nights
5-Night North America
Disney Wonder · Disney Cruise Line
Calls at Catalina Island (California) · Ensenada (Mexico)
Returns Mon, Apr 19, 2027
from $1,257 $251 a night · per person
interior, as of 2026-10-23
APR
15
Thursday · 3 nights
3-Night Ensenada
Serenade of the Seas · Royal Caribbean International
Calls at Ensenada (Mexico)
Returns Sun, Apr 18, 2027
Lowest fare shown
from $364.06 $121 a night · per person
lowest available fare, as of 2026-10-23
APR
17
Saturday · 6 nights
6-Night U.S. Pacific Coast
Eurodam · Holland America Line
Calls at San Francisco (California)
Ends in Vancouver (British Columbia)
Ends Fri, Apr 23, 2027 in Vancouver
from $949 $158 a night · per person
balcony, as of 2026-10-23
APR
17
Saturday · 7 nights
7-Night U.S. Pacific Coast
Zaandam · Holland America Line
Calls at Catalina Island (California) · Santa Barbara (California) · Astoria (Oregon) · Victoria (British Columbia)
Ends in Vancouver (British Columbia)
Ends Sat, Apr 24, 2027 in Vancouver
from $999 $143 a night · per person
interior, as of 2026-10-23
APR
18
Sunday · 4 nights
4-Night Catalina & Ensenada
Serenade of the Seas · Royal Caribbean International
Calls at Catalina Island (California) · Ensenada (Mexico)
Returns Thu, Apr 22, 2027
from $418.5 $105 a night · per person
lowest available fare, as of 2026-10-23
APR
19
Monday · 4 nights
4-Night Baja Mexico
Disney Wonder · Disney Cruise Line
Calls at Ensenada (Mexico)
Returns Fri, Apr 23, 2027
from $973 $243 a night · per person
interior, as of 2026-10-23
APR
22
Thursday · 3 nights
3-Night Ensenada
Serenade of the Seas · Royal Caribbean International
Calls at Ensenada (Mexico)
Returns Sun, Apr 25, 2027
from $381.31 $127 a night · per person
lowest available fare, as of 2026-10-23
APR
23
Friday · 7 nights
7-Night Baja Mexico
Disney Wonder · Disney Cruise Line
Calls at Puerto Vallarta (Mexico) · Cabo San Lucas (Mexico) · Ensenada (Mexico)
Returns Fri, Apr 30, 2027
from $1,554 $222 a night · per person
interior, as of 2026-10-23
APR
25
Sunday · 7 nights
7-Night Ensenada, Cabo & La Paz
Serenade of the Seas · Royal Caribbean International
Calls at La Paz (Mexico) · Cabo San Lucas (Mexico) · Ensenada (Mexico)
Returns Sun, May 2, 2027
from $659 $94 a night · per person
interior, as of 2026-10-23
APR
28
Wednesday · 4 nights
4-Night U.S. Pacific Coast
Nieuw Amsterdam · Holland America Line
Calls at Victoria (British Columbia)
Ends in Vancouver (British Columbia)
Sources disagree, verify
Ends Sun, May 2, 2027 in Vancouver
from $429 $107 a night · per person
interior, as of 2026-10-23
APR
30
Friday · 6 nights
6-Night Baja Mexico
Disney Wonder · Disney Cruise Line
Calls at Cabo San Lucas (Mexico) · Ensenada (Mexico)
Returns Thu, May 6, 2027
from $1,366 $228 a night · per person
interior, as of 2026-10-23

Narrow down April 2027

Ships this month

Lines this month

Where they go

Cruising from San Diego in April 2027

How many cruises leave San Diego in April 2027?

17 departures are scheduled, on 6 ships from 3 lines: Royal Caribbean International, Disney Cruise Line, and Holland America Line.

What is the cheapest cruise from San Diego in April 2027?

The lowest starting fare we have on record is $364.06 per person for the 3-night Serenade of the Seas sailing departing Thu, Apr 15, 2027. The average starting fare across the month is about $826 per person.

Which ships sail from San Diego in April 2027?

Serenade of the Seas (7), Disney Wonder (5), Zaandam (2), Koningsdam (1), Eurodam (1), Nieuw Amsterdam (1)

How long are the April 2027 sailings?

They run from 3 to 13 nights.