Cruise line

Crystal cruises from San Diego

Crystal has 3 departures from the Port of San Diego in the period we cover, on one ship: Crystal Serenity.

They run from 9 to 15 nights and go to the Mexican Riviera and the Sea of Cortez and other routes.

We haven't recorded fares for these sailings yet.

Crystal can move ships and change routes, and the fares here are starting prices rather than quotes. Confirm both with the line.

Crystal Serenity 3

Schedule last updated 2026-10-23 · 3 departures listed · Dates can change. Verify with the cruise line before booking.

What Crystal runs from San Diego

All routes

The 3 departures below run a smaller number of distinct itineraries. Cheapest per night first.

Distinct itineraries available, cheapest per night first
Itinerary	Ship	Nights	Departures	From
9-Night Sea of Cortez Calls at Topolobampo (Mexico) · Guaymas (Mexico) · La Paz (Mexico) Next on Mon, Dec 21, 2026	Crystal Serenity	9	1	Not recorded
9-Night Mexican Riviera Calls at Manzanillo (Mexico) · Puerto Vallarta (Mexico) · Mazatlán (Mexico) · Cabo San Lucas (Mexico) Next on Wed, Dec 30, 2026	Crystal Serenity	9	1	Not recorded
15-Night San Diego to Callao Calls at Cabo San Lucas (Mexico) · Mazatlán (Mexico) · Puerto Vallarta (Mexico) · Acajutla (El Salvador) · Playa Flamingo (Costa Rica) · Puntarenas (Costa Rica) · Manta (Ecuador) · Guayaquil (Ecuador) · Salaverry (Peru) Ends in Callao (Peru) Next on Fri, Jan 8, 2027	Crystal Serenity	15	1	Not recorded

Starting fares per person, for the cheapest cabin listed, with taxes and port fees included, checked 2026-10-23. Fares change often, so check the current price before you book.

Every departure by date

Crystal sailings from the Port of San Diego
Departs	Ship	Nights	Itinerary & ports	From
Mon, Dec 21, 2026 backWed, Dec 30, 2026	Crystal Serenity	9	9-Night Sea of Cortez Calls at Topolobampo (Mexico) · Guaymas (Mexico) · La Paz (Mexico)	Check prices
Wed, Dec 30, 2026 backFri, Jan 8, 2027	Crystal Serenity	9	9-Night Mexican Riviera Calls at Manzanillo (Mexico) · Puerto Vallarta (Mexico) · Mazatlán (Mexico) · Cabo San Lucas (Mexico)	Check prices
Fri, Jan 8, 2027 endsSat, Jan 23, 2027	Crystal Serenity	15	15-Night San Diego to Callao Calls at Cabo San Lucas (Mexico) · Mazatlán (Mexico) · Puerto Vallarta (Mexico) · Acajutla (El Salvador) · Playa Flamingo (Costa Rica) · Puntarenas (Costa Rica) · Manta (Ecuador) · Guayaquil (Ecuador) · Salaverry (Peru) Ends in Callao (Peru)	Check prices

DEC
21
Monday · 9 nights
9-Night Sea of Cortez
Crystal Serenity · Crystal
Calls at Topolobampo (Mexico) · Guaymas (Mexico) · La Paz (Mexico)
Returns Wed, Dec 30, 2026
Check prices
DEC
30
Wednesday · 9 nights
9-Night Mexican Riviera
Crystal Serenity · Crystal
Calls at Manzanillo (Mexico) · Puerto Vallarta (Mexico) · Mazatlán (Mexico) · Cabo San Lucas (Mexico)
Returns Fri, Jan 8, 2027
Check prices
JAN
8
Friday · 15 nights
15-Night San Diego to Callao
Crystal Serenity · Crystal
Calls at Cabo San Lucas (Mexico) · Mazatlán (Mexico) · Puerto Vallarta (Mexico) · Acajutla (El Salvador) · Playa Flamingo (Costa Rica) · Puntarenas (Costa Rica) · Manta (Ecuador) · Guayaquil (Ecuador) · Salaverry (Peru)
Ends in Callao (Peru)
Ends Sat, Jan 23, 2027 in Callao
Check prices

Crystal by month

December 2026 2 January 2027 1

Where these sailings go

Mexican Riviera and Sea of Cortez 2 Other itineraries 1

Cruise line website: Crystal. Confirm dates and fares there before you book.