Destinations
Where cruises from San Diego actually go
Most cruises from San Diego are short: three to five nights to Ensenada, often with a day at Catalina Island, or a week down the Mexican Riviera. The rest go further, to Hawaii, through the Panama Canal or up the coast to Vancouver, and most of those are Holland America voyages. The counts on each card come straight from the schedule.
Baja and Ensenada
Mostly three- to five-night trips to Ensenada, often with a day at Catalina Island first. The longer ones add Cabo San Lucas. Disney Wonder and Royal Caribbean's Serenade of the Seas run almost all of them.
119 sailings · 3 to 7 nights · from $219.19
Mexican Riviera and Sea of Cortez
Week-long trips down the coast to Cabo San Lucas, Mazatlán and Puerto Vallarta, or into the Sea of Cortez to La Paz. Holland America's longer ones go on to Manzanillo and Acapulco, or up the gulf to Guaymas and Topolobampo.
65 sailings · 6 to 16 nights · from $419
Pacific coast
Mostly one-way trips north to Vancouver in spring, usually with a day in Victoria on the way. Holland America also runs a few round trips that call at San Francisco and Santa Barbara.
19 sailings · 4 to 18 nights · from $399
Hawaii and South Pacific
Holland America's long voyages on Koningsdam and Zaandam. The Hawaii round trips take 17 or 18 nights and call at Hilo, Kona, Kahului, Honolulu and Nawiliwili, with Ensenada on the way home, and some are sold joined to a week in Mexico. The longest carry on to Tahiti and the Marquesas, and one goes as far as Australia.
15 sailings · 17 to 90 nights · from $1,699
Panama Canal
One-way trips through the canal, most of them ending in Miami, Fort Lauderdale, Tampa or Galveston. On the way they call along the Mexican and Central American coast, at places like Puerto Vallarta, Puerto Quetzal in Guatemala and Puntarenas in Costa Rica, and then at Cartagena in Colombia. Azamara's longest carries on across the Atlantic to England.
11 sailings · 14 to 35 nights · from $1,699
Other itineraries
One-way voyages down the Pacific coast of Central and South America. Crystal Serenity ends in Callao, the port for Lima. Holland America's Nieuw Amsterdam goes on to Chile, and the longer of its two voyages carries on through the Chilean fjords and the Falklands to Buenos Aires.
3 sailings · 15 to 36 nights · from $2,784
Starting fares per person, for the cheapest cabin listed, with taxes and port fees included, checked 2026-10-23. Fares change often, so check the current price before you book.
